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Department of Defense Serum Repository

Information on the functionality of the DoDSR and how it helps epidemiologists and preventive medicine physicians understand the causes of diseases in U.S. military service members.

The Department of Defense Serum Repository (DoDSR) was established in 1989 as the Army/Navy Serum Repository for storing serum that remained following mandatory HIV testing within the active and reserve components of the Army, Navy, and Marines. Since that time, the mission of the DoDSR has expanded to include the collection and storage of operational deployment specimens as well as Air Force specimens. Read Hidden gem strengthens cutting-edge DoD research for more information.

The DoDSR

  • Is a secure facility maintained by the Armed Forces Health Surveillance Branch (AFHSB). 
  • Currently houses more than 62 million serial blood-derived serum specimens in large state-of-the-art walk-in freezers, and continues to grow by approximately 2.0 million specimens per year.

The Mission of the DoDSR

  • To receive and store remaining serum specimens from HIV testing programs within the DoD.
  • Receive and store serum specimens related to operational deployments worldwide. 
  • Retain relevant personnel and other information on individuals serving within the military to include information on serum specimens in the repository. 

Added Value

The availability of serial serologic specimens as well as relevant demographic, occupational, and medical information within the databases at AFHSB enables the DoDSR to make significant contributions to clinical and seroepidemiologic investigations. Specimens contained in the DoDSR are available to researchers and other investigators within the DoD for the purposes of conducting militarily relevant investigations. 

Questions? Email us if you have questions regarding use of the serum repository.

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Blood and tissue samples help DoD make major contribution to Cancer Moonshot

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10/20/2016
Army Col. Craig Shriver is director of the John P. Murtha Cancer Center at Walter Reed National Military Medical Center in Bethesda, Maryland.

For more than 25 years, the military has collected and stored blood serum from all of its members and tissues from many. All that material is now playing a key role in the national Cancer Moonshot.

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Department of Defense Serum Repository

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8/3/2016
The Department of Defense Serum Repository is a longitudinal serum repository that serves as a central archive of sera drawn from Service members for medical surveillance purposes. As the world’s largest repository of its kind, the DoDSR has greatly contributed to a better understanding of the etiology of health conditions that would otherwise not be amenable to prospective study.  More on the DODSR  •	The DoDSR stores more than 60 million serial serum specimens from more than 10 million active duty and reserve service members throughout their careers. •	Since 1990, sera remaining after routine HIV-1 antibody testing and sera collected before and after major deployments have been forwarded to the DoDSR. •	All serial serum specimens stored in the DoDSR are linkable to data in the Defense Medical Surveillance System (DMSS) – the central repository of military and medical surveillance data of U.S. service members. •	At the repository, specimens are stored in precisely documented locations in walk-in freezers at -30 Celsius. •	The DoDSR adds a powerful sero epidemiological capability to overall military health surveillance with linkage of data relevant to individual characteristics, exposure states, medical events, and specimens. •	As a result, studies that used to require months to years, if feasible and affordable at all, can now be conducted in days to weeks by in-house epidemiologists.  Over time, the serum repository will increase in its value as new etiologic hypotheses are developed, as technologies for detecting biological markers in sera are improved, and as medical events accrue among aging cohorts of contributors. Follow us on Twitter for more info: @AFHSBPAGE

The Department of Defense Serum Repository is a longitudinal serum repository that serves as a cental archive of sera drawn from Service members for medical surveillance purposes.

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Preserving the Health of U.S. Armed Forces with DMSS and DoDSR

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7/13/2016
The Defense Medical Surveillance System (DMSS) and the DoD Serum Repository (DoDSR) provide unprecedented capabilities for conducting comprehensive population-based surveillance of the U.S. Armed Forces while protecting the privacy and confidentiality of service members. The systems together provide glimpses of the capabilities and potential uses of public health surveillance systems of the future.  The research advantages of the DMSS and DoDSR The DMSS and DoDSR enable researchers to focus time and attention on solving methodological problems, interpreting results, producing summaries and reports.  DMSS includes personnel data, medical data, laboratory data, deployment data, and DoDSR data. Benefactors of the DMSS and DoDSR are epidemiologists, preventive medicine doctors, data analysts, DoD policy makers, Military Commanders and public health officers. Learn how to harness the full value of the DMSS and DoDSR at www.Health.mil/AFHSB

The Defense Medical Surveillance System (DMSS) and the DoD Serum Repository (DoDSR) provide unprecedented capabilities for conducting comprehensive population-based surveillance of the U.S. Armed Forces.

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