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Hepatitis A

Hepatitis A Vaccine Resource Center

Hepatitis AHepatitis A is a liver disease caused by the hepatitis A virus (HAV). Hepatitis A virus can infect anyone, but vaccines are available for long-term protection in persons 1 year of age and older. Good personal hygiene and proper sanitation can also help prevent the spread of hepatitis A. 

Hepatitis A is most often spread by the fecal-oral route (an object contaminated with the stool of a person with hepatitis A is put into another person's mouth), or by swallowing food or water that contains the virus.

Hepatitis A vaccine is routinely recommended for all children and adolescents.  It is also recommended for people who are at increased risk for infection, such as persons traveling to countries with high rates of hepatitis A, infants (aged 6-11 months) traveling outside the United States, persons aged 1 year or older infected with human immunodeficiency virus (HIV), persons with chronic liver disease, pregnant women with increased risk for HAV infection during pregnancy, persons aged 1 year or older at risk for HAV infection during hepatitis A outbreaks, and persons providing services to adults in which a high proportion of persons have risk factors for HAV infection..

Source: Centers for Disease Control and Prevention

Resource Center

You will find below all of the resources you will need about the hepatitis A vaccine. More will be added as they are published or released.

Information Paper Date
Hepatitis A Infection and Hepatitis A Vaccines Sept. 28, 2020

Counting Doses in Combined Regimens of Monovalent and Bivalent Hepatitis A and Hepatitis B vaccines

Aug. 30, 2019
Standing Orders Date
Hepatitis A Vaccine (Pediatric)
May 18, 2023
Hepatitis A Vaccine (Adult)
May 26, 2023
Vaccine Information Statements (VIS) Date
Hepatitis A Vaccine: What You Need to Know
Oct. 15, 2021
Manufacturer Package Inserts Date
Dec. 3, 2021
Dec. 18, 2018
Oct. 23, 2020
Advisory Committee on Immunization Practices (ACIP) Recommendations Date
Hepatitis A Vaccine
July 3, 2020

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Hepatitis A Infection and Hepatitis A Vaccines

Fact Sheet

This information paper describes hepatitis A virus and the vaccines to prevent the disease.

Counting Doses in Combined Regimens of Monovalent and Bivalent Hepatitis A and Hepatitis B vaccines

Fact Sheet

This information paper describes the required number of doses, using various combinations of monovalent (single antigen) hepatitis A and hepatitis B vaccines and the bivalent (combination hepatitis A and hepatitis B) vaccine, to ensure adequate immunity against both diseases.

Increase in Hepatitis A Virus Infections — United States, 2013–2018


During 2016–2018, reports of hepatitis A infections in the United States increased by 294% compared with 2013–2015, related to outbreaks associated with contaminated food items, among men who have sex with men, and primarily, among persons who report drug use or homelessness.

Notes from the Field: Acute Hepatitis A Virus Infection Among Previously Vaccinated Persons with HIV Infection – Tennessee, 2018


During an ongoing Hepatitis A outbreak in Tennessee, it was found that previous vaccination did not reliably provide protection among some persons with HIV infection.

Notes from the Field: Hepatitis A Outbreak Associated with Drug Use and Homelessness – West Virginia, 2018


A hepatitis A outbreak among people experiencing homelessness or using drugs in West Virginia prompted a local health department to launch a vaccination campaign that included opt-out vaccination upon entry into homeless shelters; vaccinations at meal centers, drop-in centers, and other locations where services are provided to persons experiencing homelessness.

Recommendations of the Advisory Committee on Immunization Practices for Use of Hepatitis A Vaccine for Persons Experiencing Homelessness


All persons aged ≥1 year experiencing homelessness should be routinely immunized against hepatitis A virus. Vaccination of homeless persons facilitates integration of hepatitis A vaccine into routine preventive services.

Update: Recommendations of the Advisory Committee on Immunization Practices for Use of Hepatitis A Vaccine for Postexposure Prophylaxis and for Preexposure Prophylaxis for International Travel


New recommendations have been issued regarding use of Hepatitis A vaccine and immune globulin in children and adults traveling internationally.

Hepatitis A Virus Outbreaks Associated with Drug Use and Homelessness 2017


During 2017, four states reported 1,521 hepatitis A infections, mostly among persons who reported drug use or homelessness, signaling a shift in hepatitis A epidemiology from point-source outbreaks associated with contaminated food to large community outbreaks with person-to-person transmission.

Hepatitis A


Epidemics of hepatitis A threaten wartime operations, particularly in highly endemic areas and during unstable (e.g., rapidly changing) field conditions.

Notes from the Field: Increase in Hepatitis A Virus Infections — Marshall Islands, 2016–2017


A look at a recent outbreak of Hepatitis A in the Marshall Islands, where Hepatitis A vaccine is not currently included in the routine childhood immunization schedule.

Updated Dosing Instructions for Immune Globulin (Human) for Hepatitis A Virus Prophylaxis


GamaSTAN S/D, the immune globulin broduct approved for hepatitis A virus (HAV) prophylaxis, updated its prescribing information with changes to the dosing instructions for both preexposure and postexposure prophylaxis indications.

Immunization Recommendations for Disaster Response Operations

Fact Sheet

This information paper provides immunization recommendations and resources for Department of Defense (DOD) personnel supporting disaster response operations, both in CONUS and OCONUS.

ASIP Dosing Schedule for MMR and Hepatitis A and B

Fact Sheet

This fact sheet provides the dosing schedule for MMR, Varicella, Hepatitis A and Hepatitis B vaccines.

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Last Updated: May 26, 2023
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