Back to Top Skip to main content Skip to sub-navigation

USU Co-leads Largest NCAA-DOD Concussion Study in History

A doctor looks at a patient's prosthetic arm. Dr. Paul F. Pasquina examines Sgt. 1st Class Ramon Padilla’s prosthetic arm in his office at the Uniformed Services University of the Health Sciences in Bethesda, Maryland. (Photo courtesy of PBS)

Recommended Content:

Traumatic Brain Injury

Uniformed Service University’s (USU) Dr. Paul Pasquina will co-lead the next phase of the largest concussion and repetitive head impact study in history, the NCAA-U.S. Department of Defense Concussion Assessment, Research and Education (CARE) Consortium.

Pasquina, professor and chair of USU’s Department of Physical Medicine and Rehabilitation, will lead the upcoming phase, known as CARE/Service Academy Longitudinal mTBI Outcomes Study (SALTOS) Integrated Study, as principal investigator for the DoD through USU’s Center for Rehabilitation Sciences Research, coordinating engagement with the four military academies, the military’s Explosive Ordnance and Disposal school at Eglin Air Force Base, as well as the Defense Health Agency’s National Intrepid Center of Excellence for TBI and Intrepid Spirit Centers at Fort Hood, Fort Bragg, and Joint Base Lewis-McChord.

CARE is the most comprehensive and prospective study of its kind, and is the product of the historic NCAA-DOD Grand alliance created in 2014. The Consortium seeks to better understand concussion, as well as Head Impact Exposure (HIE), with broad aims to enhance the health and safety of NCAA student-athletes and military service members. It is also the first major concussion study to assess both women and men in 24 sports, and serves as a valuable resource for youth sports participants and society at large. Prior to CARE, most concussion literature came from men’s football and men’s ice hockey. Leveraging its extensive infrastructure and experienced research team, the consortium has now published more than 80 scientific papers that have been critical to advancing the science of mild Traumatic Brain Injury (mTBI)/concussion and HIE.

The initial phase of CARE focused on the six-month natural history and neurobiology of acute concussion and HIE. The second phase, CARE 2.0, prospectively investigated the intermediate effects -- such as changes in brain health outcomes over a college career -- and early persistent health effects associated with HIE and concussion soon after graduation. CARE/SALTOS will investigate the nature and causes of long-term effects of HIE and concussion/mTBI in NCAA student-athletes and military service members.

“As a former member of West Point’s varsity football team, where I sustained several concussions, my interest in this study is both personal and professional,” Pasquina said. “There remain a number of unanswered questions surrounding concussion and head impact exposure that we hope to be able to help answer through this study. Our team remains committed to help protect, promote, and preserve brain health for service members, athletes, and the public.”

The Consortium has also just received a combined $42.65 million in funding to begin the next phase of its landmark research project. The newly-awarded funding includes a $25 million award from the Medical Technology Enterprise Consortium via the U.S. Army Medical Research and Development Command, from the Defense Health Program under the oversight of the Assistant Secretary of Defense for Health Affairs. An additional $10 million in funding was awarded by the NCAA, and $7.65 million was granted by the Defense Health Agency via a Cooperative Research and Development Agreement. This latest funding will allow the research team additional resources to build upon existing CARE/SALTOS research by following former CARE research participants beyond graduation to evaluate the long-term or late effects (up to 10 years) on brain health after mTBI/concussion and/or HIE.

The CARE/SALTOS Integrated study is an integrated public/private effort, and is designed to identify the unique individual characteristics (such as phenotypes/genotypes) of individuals at a higher versus lower risk of negative outcomes associated with concussion and HIE. This data set will be made available to the broader scientific community to promote further development of specific strategies for injury prevention, early recognition, and mitigating treatments of those at greatest risk of brain health effects.

You also may be interested in...

Management of Headache Following Concussion/mTBI Clinical Recommendation

Publication
7/31/2020

This clinical recommendation outlines the assessment and management of headache following mild TBI. It includes specific recommendations regarding how health care providers can help patients manage pharmacologic and non-pharmacologic treatment of post-traumatic headache (PTH).

Recommended Content:

Traumatic Brain Injury Center of Excellence | Provider Resources | TBI Educators | Traumatic Brain Injury

Management of Sleep Disturbances Following Concussion/mTBI Clinical Recommendation

Publication
7/31/2020

This TBICoE clinical recommendation outlines how to identify and assess sleep disturbances following a concussion; primary care manager initial treatment options; and recommended conditions for referral to sleep medicine.

Recommended Content:

Traumatic Brain Injury Center of Excellence | Provider Resources | Traumatic Brain Injury | TBI Symptoms | TBI Resources

Indications and Conditions for In-Theater Post-Injury Neurocognitive Assessment Tool (NCAT) Testing

Publication
7/31/2020

This clinical recommendation provides background of pre-deployment neurocognitive testing and the use of automated neuropsychological assessment metrics (ANAM).

Recommended Content:

Traumatic Brain Injury Center of Excellence | Provider Resources | Traumatic Brain Injury | TBI Screening | TBI Resources

Management of Headache Following Concussion/mTBI Clinical Support Tool

Publication
7/31/2020

This clinical support tool uses an algorithmic approach for health care providers to help assess and manage headache in service members and veterans who sustain a mild TBI and experience post-traumatic headache (PTH). The tool offers providers a step-by-step process to determine the type of headache following mild TBI and indications for emergency or specialty referral.

Recommended Content:

Traumatic Brain Injury Center of Excellence | Provider Resources | TBI Educators | Traumatic Brain Injury

Cognitive Rehabilitation for Following Mild to Moderate TBI Clinical Recommendation - Full

Publication
7/30/2020

This TBI clinical recommendation is broken down into three primary categories: Modifications for Service Members and Veterans; Interventions and Strategies to Address Cognitive Dysfunction; and, Delivery of Rehabilitation for Patients with Cognitive Challenges. Each category contains clinical recommendations, the background and rationale behind them, evidence review references, and clinical resources.

Recommended Content:

Traumatic Brain Injury Center of Excellence | Provider Resources | TBI Educators | Cognitive Rehabilitation Therapy | Traumatic Brain Injury

Cognitive Rehabilitation Following Mild to Moderate TBI - Referring Provider Resource

Publication
7/30/2020

This resource answers common questions that referring providers may have, such as how to determine if a patient is having cognitive difficulties or whether the patient is a good candidate for cognitive rehabilitation following a mild to moderate traumatic brain injury.

Recommended Content:

Traumatic Brain Injury Center of Excellence | Provider Resources | TBI Educators | TBICoE Research | Cognitive Rehabilitation Therapy | Traumatic Brain Injury | TBI Resources

Military Acute Concussion Evaluation 2 (MACE 2)

Publication
7/30/2020

The 2018 Military Acute Concussion Evaluation 2 (MACE 2) is an acute assessment tool for all medically trained personnel who treat service members involved in a potentially concussive event. The MACE 2 incorporates current state-of-the-science traumatic brain injury information, including vestibular-ocular-motor screening. The MACE 2 is an update to and replaces the original MACE.

Recommended Content:

Traumatic Brain Injury Center of Excellence | Traumatic Brain Injury | Provider Resources | TBI Educators | TBI Screening

Cognitive Rehabilitation Following Mild to Moderate TBI Clinical Recommendation - Short

Publication
7/30/2020

This short version of the Cognitive Rehabilitation Following Mild to Moderate TBI Clinical Recommendation provides an at-a-glance overview of the full-length version for quick access and use on the job.

Recommended Content:

Traumatic Brain Injury Center of Excellence | Traumatic Brain Injury | TBI Resources | SCORE Study Manuals | Cognitive Rehabilitation Therapy
<< < 1 2 3 4 5 > >> 
Showing results 61 - 68 Page 5 of 5

DHA Address: 7700 Arlington Boulevard | Suite 5101 | Falls Church, VA | 22042-5101

Some documents are presented in Portable Document Format (PDF). A PDF reader is required for viewing. Download a PDF Reader or learn more about PDFs.