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Military Health System

Prevalence and Distribution of Refractive Errors Among Members of the U.S. Armed Forces and the U.S. Coast Guard, 2019.

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Medical Surveillance Monthly Report

Abstract

During calendar year 2019, the estimated prevalence of myopia, hyperopia, and astigmatism were 17.5%, 2.1%, and 11.2% in the active component of the U.S. Armed Forces and 10.1%, 1.2%, and 6.1% of the U.S. Coast Guard, respectively. The prevalence of spectacle correction in the active component of the U.S. Armed Forces was 24.0%, which included single-vision distance (92.0%), multifocal (eg, bifocal, 6.0%), and single-vision reading (2.0%) spec­tacles. In comparison, the prevalence of spectacle correction was 14.6% in the U.S. Coast Guard. Additionally, among all U.S. Armed Forces service members who received spectacle correction for distance vision in 2019, ser­vice members of the reserve component, military academy cadets, and the National Guard were significantly more myopic (near-sightedness) than the active component or Coast Guard (p<.001). Within the active component, the Air Force was the most myopic and the Marine Corps followed it closely. These 2 military branches were not significantly different from each other (p=.46) but both were significantly more myopic than the Navy or the Army (p<.001). The Navy was more myopic than the Army (p=.01). The U.S. Coast Guard was significantly less myopic than any other military branch (p=.03).

What are the new findings?

Warfighters with a functional unaided vision have significant advantage on the battlefield or in other operational environments. During calendar year 2019, the prevalence of refractive errors in the active component of the U.S. Armed Forces and U.S. Coast Guard were relatively low. Approximately 20% of the active component service members had substantial refractive errors that require fulltime spectacle correction.

What is the impact on readiness and force health protection?

Refractive distribution of the U.S. Armed Forces is essential for better understanding of warfighter visual capabilities, establishing vision standards and policies, and supporting acquisition and development of the next generation military
protective eyewear and devices.

Background

Uncorrected refractive error is the leading cause of visual impair­ment worldwide.1 Refractive error occurs when there is a mismatch between axial length of the eye and the refractive power produced by the cornea and the crystalline lens. The eye is myopic (near-sighted) when the eye’s axial length is longer and images of distant objects focus in front of the retina.2 Hyperopia (far-sightedness) occurs when the axial length is shorter and images of distant objects focus behind the retina.2 With a low amount of hyperopia, a younger eye (i.e., approximately under age 40) can achieve clear images through accommodation in which the ciliary mus­cles contract and cause the crystalline lens to increase its refractive power. Astigma­tism reduces quality of vision by differential magnification in each principal meridian of the cornea and/or the crystalline lens.3 It is another form of ocular aberration that induces blurred vision.3 Presbyopia is an age-related, blurred near vision due to progressive loss of accommodation (i.e., near focusing ability) that usually begins to manifest after the age of 40.4 

The prevalence of myopia, the most common type of refractive error, increased worldwide from 10.4% to 34.2% between 1993 through 20165 and in the United States from 25.0% to 41.6% between 1970 through 2000.6 Among military service members, one study describes a similar trend for Austrian military conscripts; Yang et al. reported that the prevalence of myo­pia increased from 13.8% to 24.4% between 1983 through 2017.7 

In the active component of the U.S. Armed Forces, Reynolds et al. estimated a crude lifetime prevalence of myopia was 38.5%, based on medical diagnostic codes for refractive error in the U.S. Defense Med­ical Surveillance System from 2001 through 2018.8 The study also reported a crude life­time prevalence of 12.0% for hyperopia and 32.9% for astigmatism.8 Moreover, an ear­lier study showed that 22% of the active component U.S. Army aviators and 27%–32% of the U.S. Army Reserve and National Guard members wore spectacle vision cor­rection between 1986 through 1989.9 

The distribution of refractive errors and the proportions of the U.S. Armed Forces and the U.S. Coast Guard that require spectacle vision correction are yet to be determined. The purpose of this study was to examine the prevalence and distri­bution of refractive errors and to evaluate spectacle corrections among active com­ponent U.S. Armed Forces and U.S. Coast Guard service members in 2019. Fur­thermore, the differences in mean refrac­tive corrections are examined among all U.S. Armed Forces service members who received spectacle corrections for distance vision in 2019, to include the active compo­nent, reserve component, National Guard, and military academy cadets.

Methods

This retrospective study evaluated spectacle prescriptions in the Spectacle Request Transmission System (SRTS) of the U.S. Department of Defense (DOD) dur­ing calendar year 2019. Study populations included the active component of the U.S. Armed Forces (Air Force, Army, Navy and Marine Corps) and the U.S. Coast Guard. The U.S. reserve component, National Guard, and military academy cadet popula­tions were used for comparison.  Denomi­nator data to calculate prevalence estimates were obtained from the U.S. Defense Man­power Data Center (DMDC). 

SRTS Database

The SRTS determines a member’s mili­tary service status (e.g., Navy, active duty) automatically during spectacle ordering as result of its interface with the DMDC. There were 1,701,907 spectacle orders among 390,217 active duty service mem­bers in 2019. Specifically, active duty ser­vice members who ordered spectacle correction for distance and/or near vision (n=323,753) included the active compo­nent of the U.S. Armed Forces (97.9%), the U.S. Coast Guard (1.8%), and others (i.e., non-U.S. military, 0.3%).

Each member may have one or more spectacle orders using the same spectacle prescription (e.g., clear and sunglasses, optical inserts for gas mask and military eye protection, etc.). Occasionally, different spectacle prescriptions may be used when distance and computer/reading spectacles were ordered separately (e.g., bifocal glasses for computer/reading or single vision glasses for near vision). Therefore, a spec­tacle prescription with the lowest spheri­cal power of the right eye was selected to ensure only one spectacle prescription for distance vision per service member was chosen, and spectacle prescriptions exclu­sively for near vision were excluded from refractive distribution analysis. 

As a result, the SRTS database for refrac­tive distribution analysis identified 379,254 spectacle prescriptions for distance vision in 2019, which included prescriptions for service members of the active component (83.3%), National Guard (4.9%), reserve component (3.4%), retired military mem­bers (7.2%), military academy cadets (0.8%), and others (e.g., non-U.S. military) (0.3%). Analyses describing the propor­tions of refractive errors were restricted to active component service members, includ­ing 310,765 service members from the U.S. Armed Forces and 5,768 service members from the U.S. Coast Guard. Differences in the magnitudes of mean refractive cor­rections are examined for all U.S. Armed Forces, to include service members of the reserve component (n=12,984), military academy cadets (n=3,222), National Guard (n=18,773), Air Force (n=81,163), Marine Corps (n=37,253), Navy (n=56,985), Army (n=135,364) and Coast Guard (n=5,768).

Definition 

Spectacle correction was defined as having a spectacle prescription in the SRTS. Spectacle refractive power is expressed in diopter (D) in spherical equivalent (SE), which was defined as spherical refraction plus one-half of the negative cylindrical value. A negative SE indicates refraction for myopia and a positive SE indicates refrac­tion for hyperopia. Astigmatism is shown as a negative cylinder (CYL) power. Astig­matism type was defined as With-the-Rule (minus cylinder axis 180° ± 15°), Against-the-Rule (minus cylinder axis 90° ± 15°), and Oblique (all other orientations).

Refractive error classification

SE was utilized to classify the low/moderate/high classifications for myopia and hyperopia. Based on the current sci­entific consensus of refractive errors clas­sification,2,5,10-13 myopia was classified as SE=-0.50 D and was further divided into Low (SE=-0.50 D and >-3.00 D), Moder­ate (SE=-3.00 D and >-6.00 D), and High (SE=-6.00 D) myopia. Hyperopia was defined as SE>+0.50 D that was further divided into Low (SE>+0.50 D and <+3.00 D) and High (SE=+3.00 D) hyperopia. Low Refractive Error was defined as SE>-0.50 D and =+0.50 D. Astigmatism was defined as CYL<-0.50 D that was further divided into Low (CYL<-0.50 D and >-1.50 D), Moder­ate (CYL=-1.50 D and >-2.50 D), and High (CYL=-2.50 D) astigmatism. 

Statistical analysis 

IBM SPSS Statistics for Windows, Version 21.0 (Armonk, NY: IBM Corp) was used for statistical analyses. To esti­mate the prevalence of spectacle correc­tion, counts of active-duty service members who had spectacle correction for distance and/or near vision served as numerators and DMDC population counts served as denominators. Likewise, counts of active duty members, which were grouped by refractive error classification from their spectacle prescriptions for distance vision, served as numerators and DMDC popula­tion counts served as a denominators for prevalence of refractive error calculations. 

For refractive distribution analysis, a two-tailed paired t-test was used to com­pare refractive errors between the right and left eyes and z-tests were used to compare the active component of the U.S. Armed Forces and the U.S. Coast Guard popula­tions. Analysis of variance was used to ana­lyze overall effects on refractive correction among military branches and groups. A Bonferroni post hoc test was used to adjust for multiple comparisons. Results were expressed as mean ± standard error. The statistical significance level was set at p<.05.

Results

Prevalence of spectacle correction

Assuming all members who required vision correction had ordered spectacles in 2019, the prevalence of spectacle correction was 24.0% in the active component of U.S. Armed Forces and 14.6% in the U.S. Coast Guard. The difference between the two pop­ulations was statistically significant (p<.001). Single-vision distance glasses were the most common type (92.0%) and followed by mul­tifocal (e.g., bifocal, 6.0%) and single-vison reading (2.0%) glasses in the active compo­nent of the U.S. Armed Forces. 

Prevalence of refractive errors

The prevalence of myopia (SE=-0.50 D) was 17.5%, hyperopia (SE>+0.50 D) was 2.1%, and astigmatism (CYL<-0.50 D) was 11.2% in the active component of the U.S. Armed Forces (n=310,765). In compari­son, the prevalence of myopia was 10.1%, hyperopia was 1.2%, and astigmatism was 6.1% in the U.S. Coast Guard (n=5,768).  There was a statistically significant differ­ence between the two populations (p<.001). The prevalence of high myopia (SE=-6.00 D) and high hyperopia (SE=+3.00 D) were 1.1% and 0.7% in the active component of the U.S. Armed Forces, and 0.5% and 0.4% in the U.S. Coast Guard, respectively.

Refractive distribution

The overall refractive distribution of the two active duty populations is shown in Figure 1. The right and left eyes had a small but statistically significant difference in sphere (mean difference: -0.020±0.001 D), cylinder (mean difference: 0.013±0.001 D), and spherical equivalent (mean difference: -0.013±0.001 D) refraction (p<.001). Both eyes were significantly correlated (r=0.954, 0.780, and 0.959, respectively, [p<.001]). 

The proportion of refractive errors in spherical equivalent (Figure 2) was not sig­nificantly different between the active com­ponent of the U.S. Armed Forces and the U.S. Coast Guard (p=.79). In the active component of the U.S. Armed Forces, the largest proportion of myopia was classi­fied as Low (50.8%), followed by Moder­ate (19.2%), and just 4.7% were classified as High. Similarly, a larger proportion of hyperopia was classified as Low (7.1%) ver­sus High (1.6%). The proportion of Low Refractive Error was 16.7%. Astigmatic spectacle correction (Figure 3) was 30.2% (Low), 11.3% (Moderate), and 5.8% (High). With-the-Rule astigmatism (minus cyl­inder axis 180°±15°) was 55.5%. Against-the-Rule astigmatism (minus cylinder axis 90°±15°) was 18.2%. Oblique astigmatism (all other orientations) was 26.3%.

Analysis of differences in the magni­tude of mean refractive corrections among the active component of the U.S. Armed Forces and the U.S. Coast Guard, National Guard, Reserve, and military academy cadets revealed a statistically significant difference in refractive correction among these groups (p<.001) (Figure 4). Pairwise comparison with Bonferroni adjustment showed that refractive correction for the active component of the U.S. Armed Forces or the U.S. Coast Guard was significantly less myopic (near-sightedness) than that of the National Guard, the military acad­emy cadets, and the Reserve (p<.001). In the active component of the U.S. Armed Forces, mean refractive corrections of the Air Force and of the Marine Corps were significantly more myopic than those of the Navy (p<.001) and the Army (p<.001). The Navy was more myopic than the Army (p=.01). Each military branch was more myopic than the Coast Guard (p=.03).

Editorial Comment

Prevalence of spectacle correction

Functional unaided vision is crucial in emergency, volatile, and high stress mili­tary operational environments. In agree­ment with an earlier study in which 22% of U.S. Army aviators wore spectacle correc­tion,9 the estimated prevalence of spectacle correction from the current analysis was 24.0% in the active component of the U.S. Armed Forces and 14.6% in the U.S. Coast Guard. 
The U.S. military medical require­ments, the Periodic Health Assessment for individual medical readiness, and the Pre-Deployment Health Assessment require an annual vision screening and spectacle orders (e.g., prescription glasses and lens inserts for military combat eye protec­tion/safety glasses).14-20 This study indi­cates that spectacles for vision correction were not ordered for over 3/4 of the active component of the U.S. Armed Forces. Fur­thermore, about 1/5 of those who ordered spectacles may not need fulltime vision correction because members with low refractive error or younger people with low hyperopia generally have “functional” unaided distance vision. 

Prevalence of refractive errors

The prevalence of refractive errors in the U.S. Armed Forces and the U.S. Coast Guard was low relative to the general U.S. popula­tion. This study shows that the prevalence of myopia (SE=-0.50 D), hyperopia (SE>+0.50 D), and astigmatism (CYL<-0.50 D) was 17.5%, 2.1%, and 11.2%, respectively in the active component of the U.S. Armed Forces. In comparison, a recent systematic review and meta-analysis study showed that an estimated pooled prevalence of myopia (SE=-0.50 D), hyperopia (SE>+0.50 D), and astigmatism (CYL<-0.50 D) was 11.7%, 4.6%, and 14.9% among those under age 20, and 26.5%, 30.9%, and 40.4% in those over age 30.5 The 2004 Eye Diseases Prevalence Research Group esti­mated myopia prevalence at 26.6%, 25.4%, and 16.4 % for European, North American, and Australian populations.21 

Moreover, visual impairment increases with increased magnitude of refractive errors. For instance, high myopia is much more likely to result in sight threatening visual impairments (e.g., myopic macular degeneration, retinal detachment, cataract, or open angle glaucoma) and hyperopic eyes had a 13% higher risk of early age-related macular degeneration.22-26 Results of this study show that the prevalence of patho­logic high refractive errors, i.e., high myopia (SE=-6.00 D) or high hyperopia (SE=+3.00 D), was low in the active component of the U.S. Armed Forces and U.S. Coast Guard. In comparison, the prevalence of high myopia was 2.4–4.2% in the general population, and the prevalence of high hyperopia was 1–3% of younger and 10–13% of the older Euro­pean population.12,27 

The prevalence of refractive errors in this study was low in comparison to a crude annual prevalence of 38.5% for myopia, 12.0% for hyperopia, and 32.9% for astigma­tism reported by Reynolds and colleagues.8 Different methodologies likely contribute to the major differences between the results of the two studies. The earlier study used outpatient medical encounter data and the refractive error definitions were based on International Classification of Disease (ICD) codes.8 In comparison, the current study used spectacle prescription data and relied on a more rigorous scientific consensus of refractive error classification. Another key factor is that individuals with a refractive error ICD code associated with an outpa­tient medical encounter may not necessarily require spectacle correction. 

The U.S. Armed Forces had a lower prevalence of hyperopia because this study used spectacle prescriptions (i.e., not cyclo­plegic refraction), and a majority of the mili­tary population (90.5%) in the current study were under 40 years of age. A rising preva­lence of hyperopia occurs in elderly popula­tions due to age-related lens changes.5 

Military medical policy on refractive error distribution

Vision screening prior to entering the military services contributes to the low prevalence and magnitude of refractive errors in the U.S. Armed Forces. Specifi­cally, refractive errors in excess of -8.00 D or +8.00 D spherical equivalent or astigma­tism in excess of 3.00 D are “disqualifying conditions” for entering the U.S. military.19 Additionally, the U.S. military refrac­tive surgery program may further reduce the prevalence and magnitude of refrac­tive errors by providing approximately 36,000 refractive surgeries (i.e., 18,000 ser­vice members) annually.28,29 The U.S. mili­tary refractive surgery program aims to enhance military members’ visual capa­bility by reducing or eliminating depen­dency on spectacles and contact lenses.29,30 The program impacts on refractive distri­bution in the U.S. Armed Forces require further investigation; however, the low prevalence of refractive errors in the active component U.S. Armed Forces and Coast Guard was likely a result of better access to the medical procedure. Certainly, refrac­tive surgery does not remove risks associ­ated with pathologic high refractive errors or eliminate vision correction for life. Some individuals after refractive surgery may still need mild spectacle correction due to refractive progression over time. 

Military implications and path forward

Warfighters with functional unaided vision have significant advantage on the bat­tlefield or in other operational environments. In the U.S. Armed Forces and the U.S. Coast Guard, the study showed that around 20% of the active duty members required fulltime spectacle correction for distance vision. The study results are useful in understanding of warfighter unaided visual capabilities, deter­mining the cost to the Military Health Sys­tem, and budgeting for DOD and Defense Health Agency programs, such as the mili­tary refractive surgery, military combat eye protection (MCEP), the optical fabrication enterprise, and more. 

Furthermore, the refractive distribu­tion of the U.S. Armed Forces are valuable for planning and procuring the next genera­tion MCEP or future military devices.  For instance, the U.S. Army Program Execu­tive Office Soldier may use the information for its consideration of MCEP with embed­ded prescription, which can negate the need for an additional layer of an optical insert and thus improve warfighters’ compliance, safety, and performance.31 Moreover, the study shows that the difference of refrac­tive error between the right and left eyes was nearly 1/100th of a diopter, which is too small to be “clinically significant”. Therefore, engi­neers may consider using the same optical parameters for each eye when designing or developing future visual augmentation or enhancement devices (e.g., the integrated visual augmentation system).  Astigmatic (cylindrical) correction is another important parameter for MCEP or other military devices. The prevalence of astigmatism (CYL<-0.50 D) was 11.2% of the active component of the U.S. Armed Forces and With-the-Rule astigmatism (minus cylinder axis 180°±15°) was the most common type. Cylindrical correction, especially for moderate and high astigma­tism (CYL=-1.50 D) that was approximately 4.1% of the active component of U.S. Armed Forces, can greatly improve warfighter visual capability. 

Lastly, presbyopia is less of a concern as over 90% of the active component service members were under 40 years of age. The prevalence of multifocal and reading glasses was less than 2% of the U.S. active compo­nent service members. In general, refractive distribution of the U.S. Armed Forces is essential for bet­ter understanding of warfighter visual capa­bilities, establishing vision standards and policies, and supporting acquisition and development of the next generation military protective eyewear and devices.

Strengths and limitations

The major strengths of this study are large sample size and the scientific refractive error classification, which provide a precise description of refractive distribution in the active component of the U.S. Armed Forces and the U.S. Coast Guard members. One limitation of the study is that prevalence of refractive errors calculation was under an assumption that all active duty mem­bers who needed spectacle correction had ordered one in 2019. Because some service members may have ordered their spectacle outside the observation period, the esti­mates of prevalence for all of the refractive errors may be underestimates.

Author Affiliations

Clinical Public Health and Epidemiology, U.S. Army Public Health Center, Aberdeen Proving Ground, MD (CDR Gao, LTC Truong, Dr. Taylor, Lt Col Robles-Morales, and LTC Aitken).

Acknowledgments

The authors would like to thank Ms. Barbara Fieldhausen and the Spectacle Request Transmission Sys­tem (SRTS) team from the Defense Health Agency for their work managing the SRTS­Web and its database.

References

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Refractive distribution of spectacles for distance vision correction in the active component of the U.S. Armed Forces (n=310,765) and Coast Guard (n=5,768), 2019

Proportion of refractive errors among spectacles for distance vision correction in the active component of the U.S. Armed Forces and Coast Guard, 2019

Proportion of astigmatism among spectacles for distance vision correction in the active component of the U.S. Armed Forces and Coast Guard, 2019

Refractive status of the right and left eye spectacles for distance vision correction, by service and duty status, 2019

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U.S. Marines sprint uphill during a field training exercise at Marine Corps Air Station Miramar, California. to maintain contact with an aviation combat element, teaching and sustaining their proficiency in setting up and maintaining communication equipment.  (Photo Courtesy: U.S. Marine Corps)

Among active component service members in 2018, there were 545 incident diagnoses of rhabdomyolysis likely due to exertional rhabdomyolysis, for an unadjusted incidence rate of 42.0 cases per 100,000 person-years. Subgroup-specific rates in 2018 were highest among males, those less than 20 years old, Asian/Pacific Islander service members, Marine Corps and Army members, and those in combat-specific or “other/unknown” occupations. During 2014–2018, crude rates of exertional rhabdomyolysis increased steadily from 2014 through 2016 after which rates declined slightly in 2017 before increasing again in 2018. Compared to service members in other race/ethnicity groups, the overall rate of exertional rhabdomyolysis was highest among non-Hispanic blacks in every year except 2018. Overall and annual rates were highest among Marine Corps members, intermediate among those in the Army, and lowest among those in the Air Force and Navy. Most cases of exertional rhabdomyolysis were diagnosed at installations that support basic combat/recruit training or major ground combat units of the Army or the Marine Corps. Medical care providers should consider exertional rhabdomyolysis in the differential diagnosis when service members (particularly recruits) present with muscular pain or swelling, limited range of motion, or the excretion of dark urine (possibly due to myoglobinuria) after strenuous physical activity, particularly in hot, humid weather.

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Medical Surveillance Monthly Report

Vasectomy and Vasectomy Reversals, Active Component, U.S. Armed Forces, 2000–2017

Article
3/1/2019
Sperm is the male reproductive cell  Photo: iStock

During 2000–2017, a total of 170,878 active component service members underwent a first-occurring vasectomy, for a crude overall incidence rate of 8.6 cases per 1,000 person-years (p-yrs). Among the men who underwent incident vasectomy, 2.2% had another vasectomy performed during the surveillance period. Compared to their respective counterparts, the overall rates of vasectomy were highest among service men aged 30–39 years, non-Hispanic whites, married men, and those in pilot/air crew occupations. Male Air Force members had the highest overall incidence of vasectomy and men in the Marine Corps, the lowest. Crude annual vasectomy rates among service men increased slightly between 2000 and 2017. The largest increases in rates over the 18-year period occurred among service men aged 35–49 years and among men working as pilots/air crew. Among those who underwent vasectomy, 1.8% also had at least 1 vasectomy reversal during the surveillance period. The likelihood of vasectomy reversal decreased with advancing age. Non-Hispanic black and Hispanic service men were more likely than those of other race/ethnicity groups to undergo vasectomy reversals.

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Medical Surveillance Monthly Report

Testosterone Replacement Therapy Use Among Active Component Service Men, 2017

Article
3/1/2019
Testosterone

This analysis summarizes the prevalence of testosterone replacement therapy (TRT) during 2017 among active component service men by demographic and military characteristics. This analysis also determines the percentage of those receiving TRT in 2017 who had an indication for receiving TRT using the 2018 American Urological Association (AUA) clinical practice guidelines. In 2017, 5,093 of 1,076,633 active component service men filled a prescription for TRT, for a period prevalence of 4.7 per 1,000 male service members. After adjustment for covariates, the prevalence of TRT use remained highest among Army members, senior enlisted members, warrant officers, non-Hispanic whites, American Indians/Alaska Natives, those in combat arms occupations, healthcare workers, those who were married, and those with other/unknown marital status. Among active component male service members who received TRT in 2017, only 44.5% met the 2018 AUA clinical practice guidelines for receiving TRT.

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Medical Surveillance Monthly Report

Brief Report: Male Infertility, Active Component, U.S. Armed Forces, 2013–2017

Article
3/1/2019
Sperm is the male reproductive cell  Photo: iStock

Infertility, defined as the inability to achieve a successful pregnancy after 1 year or more of unprotected sexual intercourse or therapeutic donor insemination, affects approximately 15% of all couples. Male infertility is diagnosed when, after testing both partners, reproductive problems have been found in the male. A male factor contributes in part or whole to about 50% of cases of infertility. However, determining the true prevalence of male infertility remains elusive, as most estimates are derived from couples seeking assistive reproductive technology in tertiary care or referral centers, population-based surveys, or high-risk occupational cohorts, all of which are likely to underestimate the prevalence of the condition in the general U.S. population.

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Medical Surveillance Monthly Report

Sexually Transmitted Infections, Active Component, U.S. Armed Forces, 2010–2018

Article
3/1/2019
Neisseria gonorrhoeae Photo Courtesy of CDC: M Rein

This report summarizes incidence rates of the 5 most common sexually transmitted infections (STIs) among active component service members of the U.S. Armed Forces during 2010–2018. Infections with chlamydia were the most common, followed in decreasing order of frequency by infections with genital human papillomavirus (HPV), gonorrhea, genital herpes simplex virus (HSV), and syphilis. Compared to men, women had higher rates of all STIs except for syphilis. In general, compared to their respective counterparts, younger service members, non-Hispanic blacks, soldiers, and enlisted members had higher incidence rates of STIs. During the latter half of the surveillance period, the incidence of chlamydia and gonorrhea increased among both male and female service members. Rates of syphilis increased for male service members but remained relatively stable among female service members. In contrast, the incidence of genital HPV and HSV decreased among both male and female service members. Similarities to and differences from the findings of the last MSMR update on STIs are discussed.

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Outbreak of Acute Respiratory Illness Associated with Adenovirus Type 4 at the U.S. Naval Academy, 2016

Article
2/1/2019
Malaria case definition

Human adenoviruses (HAdVs) are known to cause respiratory illness outbreaks at basic military training (BMT) sites. HAdV type-4 and -7 vaccines are routinely administered at enlisted BMT sites, but not at military academies. During Aug.–Sept. 2016, U.S. Naval Academy clinical staff noted an increase in students presenting with acute respiratory illness (ARI). An investigation was conducted to determine the extent and cause of the outbreak. During 22 Aug.–11 Sept. 2016, 652 clinic visits for ARI were identified using electronic health records. HAdV-4 was confirmed by real-time polymerase chain reaction assay in 18 out of 33 patient specimens collected and 1 additional HAdV case was detected from hospital records. Two HAdV-4 positive patients were treated for pneumonia including 1 hospitalized patient. Molecular analysis of 4 HAdV-4 isolates identified genome type 4a1, which is considered vaccine-preventable. Understanding the impact of HAdV in congregate settings other than enlisted BMT sites is necessary to inform discussions regarding future HAdV vaccine strategy.

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Update: Incidence of Glaucoma Diagnoses, Active Component, U.S. Armed Forces, 2013–2017

Article
2/1/2019
Glaucoma

Glaucoma is an eye disease that involves progressive optic nerve damage and vision loss, leading to blindness if undetected or untreated. This report describes an analysis using the Defense Medical Surveillance System to identify all active component service members with an incident diagnosis of glaucoma during the period between 2013 and 2017. The analysis identified 37,718 incident cases of glaucoma and an overall incidence rate of 5.9 cases per 1,000 person-years (p-yrs). The majority of cases (97.6%) were diagnosed at an early stage as borderline glaucoma; of these borderline cases, 2.2% progressed to open-angle glaucoma during the study period. No incident cases of absolute glaucoma, or total blindness, were identified. Rates of glaucoma were higher among non-Hispanic black (11.0 per 1,000 p-yrs), Asian/Pacific Islander (9.5), and Hispanic (6.9) service members, compared with non-Hispanic white (4.0) service members. Rates among female service members (6.6 per 1,000 p-yrs) were higher than those among male service members (5.8). Between 2013 and 2017, incidence rates of glaucoma diagnoses increased by 75.4% among all service members.

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Re-evaluation of the MSMR Case Definition for Incident Cases of Malaria

Article
2/1/2019
Anopheles merus

The MSMR has been publishing the results of surveillance studies of malaria since 1995. The standard MSMR case definition uses Medical Event Reports and records of hospitalizations in counting cases of malaria. This report summarizes the performance of the standard MSMR case definition in estimating incident cases of malaria from 2015 through 2017. Also explored was the potential surveillance value of including outpatient encounters with diagnoses of malaria or positive laboratory tests for malaria in the case definition. The study corroborated the relative accuracy of the MSMR case definition in estimating malaria incidence and provided the basis for updating the case definition in 2019 to include positive laboratory tests for malaria antigen within 30 days of an outpatient diagnosis.

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Update: Malaria, U.S. Armed Forces, 2018

Article
2/1/2019
Anopheles merus

Malaria infection remains an important health threat to U.S. service mem­bers who are located in endemic areas because of long-term duty assign­ments, participation in shorter-term contingency operations, or personal travel. In 2018, a total of 58 service members were diagnosed with or reported to have malaria. This represents a 65.7% increase from the 35 cases identi­fied in 2017. The relatively low numbers of cases during 2012–2018 mainly reflect decreases in cases acquired in Afghanistan, a reduction due largely to the progressive withdrawal of U.S. forces from that country. The percentage of cases of malaria caused by unspecified agents (63.8%; n=37) in 2018 was the highest during any given year of the surveillance period. The percent­age of cases identified as having been caused by Plasmodium vivax (10.3%; n=6) in 2018 was the lowest observed during the 10-year surveillance period. The percentage of malaria cases attributed to P. falciparum (25.9 %) in 2018 was similar to that observed in 2017 (25.7%), although the number of cases increased. Malaria was diagnosed at or reported from 31 different medical facilities in the U.S., Afghanistan, Italy, Germany, Djibouti, and Korea. Pro­viders of medical care to military members should be knowledgeable of and vigilant for clinical manifestations of malaria outside of endemic areas.

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Medical Surveillance Monthly Report

Thyroid Disorders, Active Component, U.S. Armed Forces, 2008–2017

Article
12/1/2018
Cover 1

This analysis describes the incidence and prevalence of five thyroid disorders (goiter, thyrotoxicosis, primary/not otherwise specified [NOS] hypothyroidism, thyroiditis, and other disorders of the thyroid) among active component service members between 2008 and 2017. During the 10-year surveillance period, the most common incident thyroid disorder among male and female service members was primary/NOS hypothyroidism and the least common were thyroiditis and other disorders of thyroid. Primary/NOS hypothyroidism was diagnosed among 8,641 females (incidence rate: 43.7 per 10,000 person-years [p-yrs]) and 11,656 males (incidence rate: 10.2 per 10,000 p-yrs). Overall incidence rates of all thyroid disorders were 3 to 5 times higher among females compared to males. Among both males and females, incidence of primary/NOS hypothyroidism was higher among non-Hispanic white service members compared with service members in other race/ethnicity groups. The incidence of most thyroid disorders remained stable or decreased during the surveillance period. Overall, the prevalence of most thyroid disorders increased during the first part of the surveillance period and then either decreased or leveled off.31.6 per 100,000 active component service members in 2017. Validation of ICD-9/ICD-10 diagnostic codes for MetS using the National Cholesterol Education Program Adult Treatment Panel III criteria is needed to establish the level of agreement between the two methods for identifying this condition.

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Incidence and Prevalence of the Metabolic Syndrome Using ICD-9 and ICD-10 Diagnostic Codes, Active Component, U.S. Armed Forces, 2002–2017

Article
12/1/2018
Incidence and Prevalence of the Metabolic Syndrome Using ICD-9 and ICD-10 Diagnostic Codes, Active Component, U.S. Armed Forces, 2002–2017

This report uses ICD-9 and ICD-10 codes (277.7 and E88.81, respectively) for the metabolic syndrome (MetS) to summarize trends in the incidence and prevalence of this condition among active component members of the U.S. Armed Forces between 2002 and 2017. During this period, the crude overall incidence rate of MetS was 7.5 cases per 100,000 person-years (p-yrs). Compared to their respective counterparts, overall incidence rates were highest among Asian/Pacific Islanders, Air Force members, and warrant officers and were lowest among those of other/unknown race/ethnicity, Marine Corps members, and junior enlisted personnel and officers. During 2002–2017, the annual incidence rates of MetS peaked in 2009 at 11.6 cases per 100,000 p-yrs and decreased to 5.9 cases per 100,000 p-yrs in 2017. Annual prevalence rates of MetS increased steadily during the first 11 years of the surveillance period reaching a high of 38.9 per 100,000 active component service members in 2012, after which rates declined slightly to 31.6 per 100,000 active component service members in 2017. Validation of ICD-9/ICD-10 diagnostic codes for MetS using the National Cholesterol Education Program Adult Treatment Panel III criteria is needed to establish the level of agreement between the two methods for identifying this condition.

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Adrenal Gland Disorders, Active Component, U.S. Armed Forces, 2002–2017

Article
12/1/2018
Adrenal Gland Disorders, Active Component, U.S. Armed Forces, 2002–2017

During 2002–2017, the most common incident adrenal gland disorder among male and female service members was adrenal insufficiency and the least common was adrenomedullary hyperfunction. Adrenal insufficiency was diagnosed among 267 females (crude overall incidence rate: 8.2 cases per 100,000 person-years [p-yrs]) and 729 males (3.9 per 100,000 p-yrs). In both sexes, overall rates of other disorders of adrenal gland and Cushing’s syndrome were lower than for adrenal insufficiency but higher than for hyperaldosteronism, adrenogenital disorders, and adrenomedullary hyperfunction. Crude overall rates of adrenal gland disorders among females tended to be higher than those of males, with female:male rate ratios ranging from 2.1 for adrenal insufficiency to 5.5 for androgenital disorders and Cushing’s syndrome. The highest overall rates of adrenal insufficiency for males and females were among non-Hispanic white service members. Among females, rates of Cushing's syndrome and other disorders of adrenal gland were 31.6 per 100,000 active component service members in 2017. Validation of ICD-9/ICD-10 diagnostic codes for MetS using the National Cholesterol Education Program Adult Treatment Panel III criteria is needed to establish the level of agreement between the two methods for identifying this condition.

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Medical Surveillance Monthly Report

2018 #ColdReadiness Twitter chat recap: Preventing cold weather injuries for service members and their families

Fact Sheet
2/5/2018

To help protect U.S. armed forces, the Armed Forces Health Surveillance Branch (AFHSB) hosted a live #ColdReadiness Twitter chat on Wednesday, January 24th, 12-1:30 pm EST to discuss what service members and their families need to know about winter safety and preventing cold weather injuries as the temperatures drop. This fact sheet documents highlights from the Twitter chat.

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Medical Surveillance Monthly Report | Winter Safety | Medical and Dental Preventive Care Fitness | Health Readiness & Combat Support
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