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Military Health System

TBICoE Research

TBICoE supports a network of military treatment facilities and Department of Veterans Affairs medical centers with traumatic brain injury (TBI) research initiatives, including gap-driven analyses and Congressionally-directed programs such as the Section 721 Longitudinal Study of TBI and Section 734 investigation into the effects of blast exposure on Warfighter Brain Health and Performance.

TBICoE's extensive internal and external collaborations allow for clinical innovation and research along the continuum of care of TBI—from initial injury to acute and post-acute medical settings; rehabilitation; and ultimately a return to family, community, and work or continued duty.  

Beyond conducting research, TBICoE also periodically reviews available peer-reviewed scientific literature to summarize the state-of-the-science, consensus of medical approaches, as well as existing and new evidence of TBI research. Many of those documents are showcased below.

TBICoE Research Gaps and Priorities (2022-2024)

TBICoE Information Papers

The Impact of Mild Traumatic Brain Injury on the Autonomic Nervous System

The purpose of this information paper is to provide a general overview of the current evidence related to the impact of concussion, or mild traumatic brain injury, on the autonomic nervous system (ANS). This paper will focus on heart rate variability, pupillary light reflex, and hyperhidrosis within the military and civilian populations.

Thumbnail image of the downloadable Information Paper on the Impact of mTBI on the Autonomic Nervous SystemDownload this information paper to learn more about the state-of-the-science of how the autonomic nervous system is impacted by mild TBI. Researchers and clinicians can learn about current tools used to measure ANS and their current clinical utility at this time.

TBICoE Research Reviews

The following TBICoE research reviews are fluid areas of investigation and provide an overview on specific topics of interest related to TBI research. These reviews will be updated as new research emerges.

Multiple Traumatic Brain Injury/Multiple Concussion

Mild Traumatic Brain Injury and Posttraumatic Stress Disorder

Chronic Traumatic Encephalopathy

TBICoE Congressional Reporting

Many of TBICoE’s drivers include mandates from Congress within the National Defense Authorization Act (NDAA). In response to and in accordance with the requirements of these mandates, a number of reports have been submitted to Congress and are available in the public record.

NDAA FY20 Sec 750 Report to Congress: Study and Report on Traumatic Brain Injury Mitigation Efforts

A study and report on TBI mitigation efforts. This report summarizes the DOD’s findings that assessed 30 unique TBI treatments published between 2015 and 2020, and provides a roadmap addressing TBI mitigation efforts.

NDAA FY19 on Chronic Traumatic Encephalopathy

A study and report on Chronic Traumatic Encephalopathy (CTE) research in the military. This report summarizes key knowledge gaps between CTE and traumatic brain injury, and outlines CTE-relevant initiatives pursued through research collaborations across Government agencies, academia, and leading research institutions.

NDAA FY18 Sec 734 Report to Congress: Longitudinal Medical Study on Blast Pressure Exposure of Members of the Armed Forces

Longitudinal medical study on Blast Exposure Pressure of Members of the Armed Forces. The Section 734 Program is inclusive of the following mandates: NDAA FY18 Section 734, NDAA FY19 Section 253, NDAA FY20 Section 717, and NDAA FY20 Section 742.

NDAA FY07 Sec 721 Report to Congress: Longitudinal Study on Traumatic Brain Injury Incurred by Members of the Armed Forces in OIF/OEF

Fifteen-year longitudinal study on health effects related to TBI incurred by members of the Armed Forces in OIF/OEF and their families.

TBICoE Publications

Since 1992, TBICoE has published over 700 peer reviewed manuscripts in collaboration with other institutions, which actively align and respond to trends, gaps, and priorities of the Defense Health Agency or broader Department of Defense to inform policy, resource management, and state of the science for warfighters, veterans, their families and caregivers, and healthcare providers.

You also may be interested in...

2022 TBICoE Annual Report

Publication
3/21/2023

The Traumatic Brain Injury Center of Excellence Annual Report provides an overview of accomplishments and activities in calendar year 2022.

Recommended Content:

Traumatic Brain Injury Center of Excellence | DOD TBI Worldwide Numbers | TBI Provider Resources | TBI Patient and Family Resources | TBI Educators | TBICoE Research

TBICoE Research Review: Chronic Traumatic Encephalopathy

Publication
3/17/2023

The purpose of this Research Review is to summarize current peer-reviewed scientific literature and expert assessment regarding the pathology, genetic pre-disposition, causes, clinical manifestations, and neuroimaging of chronic traumatic encephalopathy.

Recommended Content:

Traumatic Brain Injury Center of Excellence | TBICoE Research | TBI Provider Resources | Provider Education | TBI Educators | TBICoE Podcasts

Chronic Traumatic Encephalopathy (CTE) Frequently Asked Questions

Fact Sheet
3/15/2023

This fact sheet provides answers and information to commonly asked questions about chronic traumatic encephalopathy, or CTE.

Recommended Content:

Traumatic Brain Injury Center of Excellence | TBICoE Research | TBI Provider Resources

INFORMATION PAPER: The Impact of Mild Traumatic Brain Injury on the Autonomic Nervous System

Publication
3/15/2023

The purpose of this information paper by TBICoE is to provide a general overview of the current evidence related to the impact of concussion/mild traumatic brain injury (mTBI) on the autonomic nervous system (ANS). This paper will focus on heart rate variability (HRV), pupillary light reflex (PLR), and hyperhidrosis within the military and civilian populations.

Recommended Content:

Traumatic Brain Injury Center of Excellence | TBICoE Research | TBI Provider Resources | TBICoE Podcasts

Optimizing Warfighter Brain Health and Performance

Video
2/21/2023
Thumbnail image of TBICoE's Dr. Sloley video.

Traumatic Brain Injury Center of Excellence research support cell chief, Dr. Stephanie Sloley, discusses her role in the organization and the importance of collaborative efforts in examining traumatic brain injuries. Dr. Sloley discusses the mission and vision of TBICoE and the importance of optimizing warfighter brain health and performance.

Recommended Content:

Traumatic Brain Injury Center of Excellence | TBICoE Research | Education & Training Events | TBI Educators | Be a Brain Warrior: Protect. Treat. Optimize.

2000-2022 Q2 DOD Worldwide Numbers for TBI

Report
11/9/2022

TBICoE is the Defense Department’s office of responsibility for tracking traumatic brain injury data in the U.S. military. Here you’ll find data on the number of active-duty service members—anywhere U.S. forces are located—with a first-time TBI diagnosis from calendar year 2000 through the second quarter of 2022. The data is also broken down by each branch of the armed services.

Recommended Content:

Traumatic Brain Injury Center of Excellence | DOD TBI Worldwide Numbers | TBI Provider Resources | TBI Educators | TBICoE Research | Armed Forces Health Surveillance Division

2022 (Q2) DOD Worldwide Numbers for TBI

Report
11/9/2022

TBICoE is the Defense Department’s office of responsibility for tracking traumatic brain injury data in the U.S. military. Here you’ll find data on the number of active-duty service members—anywhere U.S. forces are located—with a first-time TBI diagnosis in the calendar year 2022 through the second quarter. The data is also broken down by each branch of the armed services.

Recommended Content:

Traumatic Brain Injury Center of Excellence | DOD TBI Worldwide Numbers | TBI Provider Resources | TBI Educators | TBICoE Research | Armed Forces Health Surveillance Division

2022 (Q1) DOD Worldwide Numbers for TBI

Report
8/24/2022

TBICoE is the Defense Department’s office of responsibility for tracking traumatic brain injury data in the U.S. military. Here you’ll find data on the number of active-duty service members—anywhere U.S. forces are located—with a first-time TBI diagnosis in the first quarter of calendar year 2022.

Recommended Content:

Traumatic Brain Injury Center of Excellence | TBICoE Research | TBI Educators

2000-2022 (Q1) DOD Worldwide Numbers for TBI

Report
8/24/2022

TBICoE is the Defense Department’s office of responsibility for tracking traumatic brain injury data in the U.S. military. Here you’ll find data on the number of active-duty service members—anywhere U.S. forces are located—with a first-time TBI diagnosis from calendar year 2000 through the first quarter of 2022. The data is also broken down by each branch of the armed services.

Recommended Content:

Traumatic Brain Injury Center of Excellence | TBICoE Research | TBI Educators

2021 Traumatic Brain Injury Center of Excellence Annual Report

Publication
4/26/2022

The 2021 Traumatic Brain Injury Center of Excellence (TBICoE) Annual Report provides a look at accomplishments and activities from calendar year 2021.

Recommended Content:

Traumatic Brain Injury Center of Excellence | TBI Educators | TBICoE Research | TBI Provider Resources

TBICoE 2021 Publications

Publication
3/16/2022

Master list of 2021 TBICoE articles published in research journals

Recommended Content:

Traumatic Brain Injury Center of Excellence | TBI Patient and Family Resources | TBICoE Research

TBI Hot Topics Bulletin March 2021

Publication
3/24/2021

Are you a busy health care provider? Not enough time to keep up with the latest TBI research trends and news? Stay informed with the TBI Hot Topics Bulletin. TBICoE tracks the latest TBI scientific studies, advances, and discoveries most relevant to health care providers. This issue covers the fourth quarter of calendar year 2020.

Recommended Content:

Traumatic Brain Injury Center of Excellence | TBICoE Research | TBI Provider Resources

TBICoE 2020 Publications

Publication
2/25/2021

Master list of 2020 TBICoE Research Publications.

Recommended Content:

Traumatic Brain Injury Center of Excellence | TBICoE Research | TBI Provider Resources

DHA’s TBI-focused Caregiver & Family Member Study continues at TBICoE

Article
2/19/2021
A husband, wife, and two children sitting at the Warrior and Family Support Center

TBICoE and NICoE continue with the Caregiver and Family Member Study.

Recommended Content:

Traumatic Brain Injury Center of Excellence | DOD TBI Worldwide Numbers | TBI Patient and Family Resources | TBICoE Research | TBICoE Podcasts | A Head for the Future

2011 DoD Worldwide Numbers for TBI

Publication
8/10/2020

DVBIC is the Defense Department’s office of responsibility for tracking TBI data in the U.S. military. On this page you’ll find annual and quarterly reports that provide data on the number of active-duty service members — anywhere U.S. forces are located — with a first-time TBI diagnosis since 2000.

Recommended Content:

Traumatic Brain Injury Center of Excellence | DOD TBI Worldwide Numbers | TBI Educators | TBI Patient and Family Resources | TBI Provider Resources | TBICoE Research | A Head for the Future | Armed Forces Health Surveillance Division | Defense Medical Surveillance System | Surveillance Case Definitions
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Last Updated: March 16, 2023
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