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Hepatitis B

Hepatitis BHepatitis B is a liver infection caused by the hepatitis B virus (HBV). Hepatitis B is transmitted when blood, semen, or another body fluid from a person infected with the virus enters the body of someone who is not infected. This can happen through sexual contact; sharing needles, syringes, other injection equipment; or from mother to baby at birth.

For many, especially children, hepatitis B infection is asympomatic. For some people, including most infected in infancy, hepatitis B can become a long-term, chronic infection. Chronic hepatitis B can lead to serious health issues, like cirrhosis or liver cancer.

The first dose of hepatitis B vaccine is given at birth, with the three-dose series completed between 6 and 18 months of age. Older children and adolescents who did not previously receive the hepatitis B vaccine should be immunized.

Source: Centers for Disease Control and Prevention

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Hepatitis B

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11/1/2018

Hepatitis B degrades the health and military operational capabilities of those affected and demands significant health care resources for its clinical management.

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Counting Doses in Combined Regimens of Monovalent and Bivalent Hepatitis A and Hepatitis B vaccines

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This information paper describes the required number of doses, using various combinations of monovalent (single antigen) hepatitis A and hepatitis B vaccines and the bivalent (combination hepatitis A and hepatitis B) vaccine, to ensure adequate immunity against both diseases.

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Community-Based Services to Improve Testing and Linkage to Care Among Non–U.S.-Born Persons with Chronic Hepatitis B Virus Infection — Three U.S. Programs, October 2014–September 2017

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5/18/2018

The CDC funded three programs to develop hepatitis B testing and linkage-to-care programs serving non–U.S.-born persons during 2014–2017; 78% of persons with chronic HBV infection were linked to care using community-based services.

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Recommendations of the Advisory Committee on Immunization Practices for Use of a Hepatitis B Vaccine with a Novel Adjuvant

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In November 2017, a single-antigen Hepatitis B vaccine with a novel immunostimulatory sequence adjuvant was approved by the Food and Drug The Advisory Committee on Immunization Practices (ACIP) has recommended this vaccine for use in persons aged ≥18 years.

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Hepatitis B ACIP Guidelines

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Notes from the Field: False-Negative Hepatitis B Surface Antigen Test Results in a Hemodialysis Patient — Nebraska, 2017

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In March 2017, a hemodialysis clinic reported a patient who had tested negative for hepatitis B virus (HBV) surface antigen (HBsAg) after vaccination in 2010 and who later tested positive for HBsAg. A public health investigation subsequently determined that the false-negative results were caused by a surface antigen mutation.

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Notes from the Field: Increase in Acute Hepatitis B Infections — Pasco County, Florida, 2011–2016

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An increase in acute hepatitis B virus infections in Florida led to targeted outreach for testing and vaccination programs for persons at high risk, and resulted in the administration of more than 300 doses of hepatitis B vaccine.

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Prevention of Hepatitis B Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices

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This report updates and summarizes previously published recommendations from the Advisory Committee on Immunization Practices (ACIP) and CDC regarding the prevention of Hepatitis B virus infection in the United States.

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Immunization Recommendations for Disaster Response Operations

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ASIP Dosing Schedule for MMR and Hepatitis A and B

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This fact sheet provides the dosing schedule for MMR, Varicella, Hepatitis A and Hepatitis B vaccines.

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